2011年1月27日木曜日

Gangrene

In recent years, Russia has seen a significant increase in incidence of atherosclerosis obliterans. Among all causes of death atherosclerotic lesions of the cardiovascular system are the first place. In this disease is the deposition of cholesterol plaques in the walls of the arteries, then these plaques penetrate calcium, and they begin to resemble the density of the stone.

Lumen of blood vessels decreases sharply, the blood flow to tissues and organs becomes insufficient. Such a condition called chronic ischemia. Depending on where the greatest vascular lesions produce chronic cerebral ischemia, which leads to strokes, coronary heart brand viagra disease and, finally, chronic lower limb ischemia. On this localization of atherosclerosis should be more detail. Symptoms of chronic lower limb ischemia are marked by different estimates of 7.5% of the male population as a whole and 35% in the older age group.

Initially, patients note fatigue of leg muscles during intensive activity (running, long walking, climbing stairs). If you do not establish a diagnosis and begin proper treatment, the disease is entering the stage of intermittent claudication. In this case, the patient is forced to stop when passing a certain distance. When this distance is greater than 200 meters, you can stop the progression of the disease correctly chosen treatment. When reducing the distance traveled by up to 100 meters or less the question of surgical treatment. Without treatment, atherosclerosis of lower limb arteries leading to disability in 30-50% of patients. In the final stage of the disease appear unbearable pain in the affected limb at rest, patients lose sleep and can come gangrene of the foot, with the inevitable amputation.

More dramatic things happen, if the atherosclerotic plaque is the cause of acute arterial thrombosis. If it affects the blood vessels of the brain is developing stroke, coronary artery - myocardial infarction, limb arteries - gangrene. In these cases, emergency surgery and therapeutic services can be effective only in half of cases.

Successful fight against atherosclerosis obliterans depends on two main points:

1. Early diagnosis, which can only assign a vascular surgeon. It involves the successive actions (inspection specialist, Doppler ultrasound, etc.).

2. Appointment depending on the stage of disease drug or surgical treatment.

Therapeutic treatment is aimed at restoring the vessel walls, reducing the risk of thrombosis, increase in oxygen consumption bodies. In the surgical treatment of thrombosed vessels are replaced with artificial ones, which are fully or partially restore blood flow to diseased organs and limbs.

Early treatment can save a full life for many years in 90-95% of patients with atherosclerosis obliterans and avoid life-threatening complications.

sensitivity to sodium
sympathetic activation
opposite effect
quantitative and qualitative
hormones

0 件のコメント:

コメントを投稿